Combining weed prevention and control tactics may result in successful weed management that is less dependent on herbicides. Some significant benefits to reducing herbicide use are lowered production costs and the ability to counter herbicide resistance. This article by Randy Anderson (USDA ARS) compares the effectiveness of weed control tactics in dryland wheat-summer fallow rotations to dryland continuous cash crop rotations on the U.S. High Plains. The dryland continuous cash crop rotations have an advantage in weed control because a wider selection of weed control tactics can be used. Weed control tactics from dryland continuous cash crop rotations can be broadly applied to other cropping systems in a range of geographic areas for effective weed control that is less herbicide dependent.